个人简介:
宋土生,男,1956年6月生。西安交通大学医学院细胞生物学与遗传学系教授。1980年毕业于陕西师范大学生物系;1998年10月至1999年10月在瑞典隆德大学医学院访问学习。目前主要研究方向:肿瘤及单基因遗传病的基因治疗。先后参与、主持承担了4项国家自然科学基金课题。近年来在国内外期刊杂志上发表论文30余篇。
现任中华医学会陕西省医学遗传学分会主任委员;中华医学会医学细胞生物学分会常务理事。
代表性论著:
1. Yu Yao, Chen Huang, Zong-Fang Li, Ai-Ying Wang, Li-Ying Liu,Xiao-Ge Zhao, Yu Luo, Lei Ni,Wang-Gang Zhang, Tu-Sheng Song. Exogenous phosphatidylethanolamine induces apoptosis of human hepatoma HepG2 cells via bcl-2/bax pathway. World J Gastroenterol 2009 April 14; 15(14): 1751-1758
2. Zhang G, Sun L, Li Z, Si L, Song T, Huang C,Zhang W. HPV-16E6 can induce
multiple site phosphorylation of p53. ONCOLOGY REPORTS, 2009; 21: 371-377.
3. Sun L, Zhang G, Lei T, Huang C,Song T, Si L.Two different HPV-11E6 fusion
proteins trap p53 in the cytoplasm and induce apoptosis.Cancer Biol Ther. 2008 Dec 26;7(12):1909 - 1915.
4. Sun L, Zhang G, Li Z, Huang C, Song T, Si L. In GFP with high risk HPV-18E6
fusion protein expressed 293T and MCF-7 cells, the endogenous wild-type p53 could be transiently phosphorylated at multiple sites.J Exp Clin Cancer Res. 2008 Sep 8;27(1):35.
5. Huang C, Liu LY, Li ZF, Wang P, Ni L, Song LP, Xu DH, Song TS. Effects of small interfering RNAs targeting MAPK1 on gene expression profile in HeLa cells as revealed by microarray analysis. Cell Biol Int. 2008,32:1081-1090(SCI)
6. L Sun,G Zhang, Z Li, T Lei, C Huang, T Song, and L Si. Celluar distribution of tumour suppressor protein P53 and high-risk human papillomavirus(HPV)-18 E6 fusion protein in wild-type p53 cell lines.J Int Med Res,2008,36(5):1015-1021
7.Detection of CCND1 amplification using laser capture microdissection coupled with real-time polymerase chain reaction in human esophageal squamous cell carcinoma.Cancer Genetics and Cytogenetics, 2007,175:19-25
著作:
主译:《生物技术与遗传工程词典》世界图书出版公司 2008年1月
联系方式:
电话:029-82657658(办)
E-mail: tusheng@mail.xjtu.edu.cn
通信地址:西安市雁塔西路76号(邮编710061)